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Accueil du site > Jobs - PostDoc - These > Engineer position : Computational Analysis, Visualization and Modeling of Redox Signaling Networks

Engineer position : Computational Analysis, Visualization and Modeling of Redox Signaling Networks

par Secretaire - 15 septembre 2016

Project description

The purpose of this project is to develop a bioinformatics tool for the visualization of massive proteomic datasets of redox signaling networks. These are made understandable through a large and high-resolution visualization wall to analyze the network dynamics, based on quantitative and time-resolved proteomic technology allowing detection of nitrosylation and glutathionylation. Structural interpretations will be enabled through an automated modeling pipeline linking to several human mitochondrial diseases.We are seeking a highly motivated candidate to design and implement a next generation bioinformatics visualization platform. The candidate will develop a tool for modeling the 3D structure of all modified proteins. The generated data will feed into visualization of the redox network circuitries. We will achieve this through a graphical representation of the redox system and its temporal evolution with the possibility to explore interconnections between different systems.Project foundations were previously established (see e.g. UnityMol), providing a well-defined framework to get started. This position is a unique training opportunity in a multi-disciplinary environment combining several leading groups in academic research.

More information here : http://www.baaden.ibpc.fr/ns16/inge...